The project will deal with the Analysis of Neuronal Populations Derived from Human iPS cells (hiPSCs) with deletions/duplications at the 16p11.2 chromosomal region. Carriers at 16p11.2 locus are characterised by neurodevelopmental symptoms such as intellectual disability and autism. Several established iPSC lines will be differentiated toward cortical and subcortical lineages to determine alterations in the differentiation programme. Transcriptomic and proteomic analyses will be included.
Department of Biology and Biotechnologies “Lazzaro Spallanzani”, University of Pavia, Pavia, Italy
3-year postdoctoral position with a scholarship starting from March 2023 (annual gross salary: Euros 25,000)
Candidates may submit their application by December 15th, 2022, through the web portal: https://pica.cineca.it/unipv
PICA Competition Code: dbb-2022-b15
Direct Link: https://pica.cineca.it/unipv/dbb-2022-b15/
Perspective candidates may contact the supervisor, Prof. Riccardo Brambilla, for informal enquiries, before submitting the application.