Virus–Host Interaction and Cell Restriction Mechanisms Viral diseases are becoming a major public health concern and an extended field of research. Deciphering the mechanisms that allow viruses to enter susceptible host cells, hijack cellular pathways, and evade innate [...]
Epigenetics and Molecular Genetics of Rare Tumors About this Research Topic Our knowledge of epigenetics and molecular genetics of rare tumors has increased very rapidly in the last few years. Innovative data on epigenetics and molecular genetics [...]
Antioxidants in Mitochondrial Dysfunction Disease We are leading the following Special Issue entitled “Antioxidants in Mitochondrial Dysfunction Disease” in the journal Antioxidants. Mitochondria act as master regulators inside our cell. While influencing the intracellular availability of [...]
Microenvironment Signals in Malignant B Cells B-cell malignancies are a heterogeneous group of hematological neoplasms derived from cells at different stages of B-cell development. Malignant B cells develop in specialized tissue microenvironments, such as bone marrow and secondary [...]
Skeletal Muscle Differentiation and Epigenetics Skeletal myogenesis is a well-characterized process, both as regards the developmental phases of muscle formation and the adult phase of muscle regeneration. The commitment of mesodermal precursors to the myogenic lineage and [...]
Multileveled Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa II Generally, photoreceptor cell survival is ensured by retinal pigment epithelium (RPE), which provides many vital functions, such as phagocytosis of photoreceptor outer segments, metabolite transport, photoreceptor [...]
Genetics and Epigenetic Mechanisms of the Neurovascular Unit Maintenance of Neurovascular Unit (NVU) integrity is essential for homeostasis of the central nervous system (CNS), and it is ensured by a multicellular bidirectional crosstalk. Several secreted neurotrophic and [...]
The Convergence of Biology and Technology: Enabling the Rise of Precision Medicine in Renal Diseases There has been a vast increase in the availability of therapeutic options in every field of medicine. The bulk of such plurality [...]
DNA Methylation in Cancer DNA methylation alterations underlie the carcinogenic process from its earliest stages. This is characterized by global losses of DNA methylation coupled with localized ectopic gains of DNA methylation at CpG islands, which [...]
Satellite DNAs: From Cellular Functions to Diseases Satellite DNAs contribute significantly to form the genome architecture of every eukaryote. The mechanism about the origin, evolution and maintenance of satellite DNA is still poorly understood but certainly this [...]
