Research fellow dal 1 marzo 2024 per un progetto presso il Dipartimento di Medicina Sperimentale (DIMES), Università degli Studi di Genova.

Impiego di EVs da cellule progenitrici umane in un modello preclinico di fibrosi cardiaca umana su microchip

We are looking for a Candidate willing to work on a project recently funded by the MUR programme PRIN PNRR entitled: “RECOVERY: pREcise Cardiac Organ-on-chip modeling to improve extracellular VEsicle-based paracrine therapy against myocardial Injury”.

The project focuses on pin pointing the anti-fibrotic and pro-regenerative effects of extracellular vesicles (EVs) secreted by human perinatal progenitors and delivered via an optimized injectable hydrogel system to a fully human cardiac organ-on-chip model where human iPSC-derived cardiac micro-tissues can be induced to a fibrotic phenotype.

This interdisciplinary project combines stem cell biology, paracrine effects, tissue engineering and biomedical engineering and it will be developed in close collaboration with Prof. Marco Rasponi, from Politecnico di Milano and Prof. Valeria Chiono from Politecnico di Torino, as RECOVERY PI and other Partner, respectively.

The Candidate will benefit from the dynamic environment of the labs of the Experimental Biology Unit at the Department of Experimental Medicine, School of Medicine of the University of Genova, located within IRCCS Ospedale Policlinico San Martino area in central Genova. The research group has access to state-of-the-art equipment including imaging, flow cytometry and NGS facilities.

Interested candidates should send their CV, a brief statement of research interest, and two names of references with contact information as soon as possible to Prof. Bollini: sveva.bollini@unige.it

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