– Molecular mechanisms underlying the regulation of human gene expression in different cells including hepatocytes and macrophages. Looking more specifically at transcriptional regulation we are interested in both epigenetic mechanisms and transcription factors.
– mitochondrial epigenetics
-Interplay between gene expression and cellular signalings mainly focusing on macrophage activation.
– Transcriptional regulation of human genes encoding metabolic enzymes in physiological and pathological conditions.
Keywords: gene expression, transcriptional regulation, mitochondria, epigenetics, hepatocytes, macrophage activation.