Università degli studi di Napoli – Federico II
Last Update: September 22, 2019
University Professors in Experimental Biology (BIO/13)
PROFESSOR
POSITION
AIBG
Stefano Bonatti – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
PO
AIBG Member
Massimo Mallardo – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
PA
AIBG Member
Simona Paladino – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
PA
AIBG Member
Daniela Sarnataro – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
PA
AIBG Member
Chiara Zurzolo – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
On leave for scientific reasons (direction of laboartory at Pasteur Institute, Paris)
PA
Maurizio Renna – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
RTD-B
AIBG Member
Massimo D’Agostino – Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM)
RTD-A
AIBG Member
PO (Professore Ordinario / Full professor)
PA (Professore Associato / Associate Professor)
RTI (Ricercatore a Tempo Indeterminato / Assistant Professor)
RTD-A (Ricercatore a Tempo Determinato – Junior / Fixed-term Junior Assistant Professor)
RTD-B (Ricercatore a Tempo Determinato – Senior / Fixed-term Senior Assistant Professor)
Fellows in Experimental Biology (BIO/13)
FELLOW
POSITION
AIBG
Elena Amendola – Dipartimento di Biologia
A
Valeria Lucci – Dipartimento di Biologia
A
Martina Addeo – Dipartimento di Biologia
D
Carmen Caiazza – Dip Medicina Molecolare e Biotecnologie Mediche (DMMBM)
D
Lucrezia Zerillo – Dip Medicina Molecolare e Biotecnologie Mediche (DMMBM)
D
Rita Genesio – Dip Medicina Molecolare e Biotecnologie Mediche (DMMBM)
B
Nunzia Mollo – Dip Medicina Molecolare e Biotecnologie Mediche (DMMBM)
B
Gemma Natale – Dip Neuroscienze, Scienze Riproduttive ed Odontostomatologiche
B
A (Assegnista di Ricerca / Post-Doctoral Fellow)
D (Dottorando / PhD Student)
B (Borsista / Fellow)
T (Tutor)
Research
Research Group 1
Stefano Bonatti
Maurizio Renna
Massimo D’Agostino
Gabriella Caporaso (Technician)
Research Themes
- Bonatti: Development peptides pharmacologically active for the most frequent Wilson disease-causing ATP7B mutant
Keywords: ATP7B, copper transporter, Wilson disease.
- Renna: Identification of novel intracellular pathways regulating mammalian autophagy in health and disease
Keywords: autophagy, neurodegenerative diseases, intracellular trafficking, cell stress responses
- D’Agostino: Identification of molecular machinery controlling organelles size in health and disease.
Keywords: Lysosomes, membrane fusion-fission, membrane trafficking, cellular clearance, secretion.
Research Group 2
Maria Vittoria Barone
Research Themes
- Molecular bases of celiac disease.
Keywords: Gliadin, endocytosis, vescicular trafficking, tissue transglutaminase, celiac disease, immune response.
Research Group 3
Maria Antonietta De Matteis
Research Themes
- Signalling in membrane trafficking
- Mendelian Disorders of membrane trafficking: molecular mechanisms and drug target identification
Keywords: Membrane trafficking, phosphoinositides, mendelian disorders, Oculocerebrorenal syndrome of Lowe (OCRL), spondylo-epiphyseal dysplasia (SED).
Research Group 4
Cinzia Di Marino
Research Themes
- Biological activity of compounds extracted from plants
Keywords: Bioactive compounds, medicinal herbs, functional foods.
Research Group 5
Geppino Falco
Elena Amendola
Valeria Lucci
Martina Addeo
Verma Henu
Research Themes
- Ontogenesis and cell specification
Keywords: Stem cells, Differentiation, Morphogens, Endoderme, Pancreas.
Research Group 6
Corrado Garbi
Research Themes
- Control of centrosome organization and ciliogenesis by c-AMP-dependent pathways.
- Rac1 regulation of junctions stability in epithelial cells
Keywords: cAMP , AKAP, primary cilium, GTPase, E-cadherin.
Research Group 7
Massimo Mallardo
Carmen Caiazza
Nora Giello
Research Themes
- Non-coding RNA in tumorigenesis
- Thyrotoxic effect of BPA in vitro ed in vivo and efficacy of the use of gene expression profiles in different model species
Keywords: non-coding RNA, cancer, gene expression, environmental pollution.
Research Group 8
Diego Luis Medina Sanabria
Research Themes
- Role of TRPML1 and lysosomal calcium signalling in autophagy and identification of TRPML1 interactors involved on lysosomal function and signalling;
- Discovery of compounds activating TRPML1-dependent pathways to treat human diseases characterized by lysosomal/autophagic dysfunction.
Keywords: TRPML1, lysosomes, lysosomal calcium signalling, autophagy, drug screening, lysosomal storage diseases.
Research Group 9
Lucio Nitsch
Antonella Izzo
Nunzia Mollo
Maria Charalambous (INCIPIT Ph.D.)
Gaetano Calì (CNR Researcher)
Research Themes
- Molecular and cellular mechanisms by which the trisomy of chromosome 21 causes the Down syndrome, and possible therapeutic approaches.
Keywords: trisomy 21, mitochondrial dysfunction, NRIP1, PGC-1 alfa, mitochondrial fission and fusion.
Research Group 10
Simona Paladino
Lucrezia Zerillo
Gemma Natale
Valentina Tinelli
Michele Picciocchi
Isabella Ferrante
Teresa Brancaccio
Tiago Vieira (Erasmus Student)
Research Themes
- Membrane trafficking in health and disease:
- Role of endosomal trafficking in neurological disorders (genetic form of Parkinson’s disease and CMT4J)
- Molecular mechanisms controlling the trafficking, membrane organization and functions of GPI-proteins in normal and cancer epithelial cells.
Keywords: membrane trafficking, endolysosomal pathway, neurological disorders (genetic forms of Parkinson disease, CMT4J), phosphoinositides, GPI-anchored proteins.
Research Group 11
Daniela Sarnataro
Antaripa Bhattacharya
Elena Petrillo
Luca Cozzone
Adriana Limone
Research Themes
- Dysfunctions of membrane trafficking and protein folding in the pathogenesis of prion and prion-like Alzheimer’s disease
- Effects of laminin receptor inhibitors on the prion-like misfolding mechanism in prion and Alzheimer’ disease
Keywords: intracellular trafficking, prion diseases, Alzheimer’s disease, folding, lipid rafts.
Research Group 12
Mariano Stornaiuolo
Research Themes
- Mechanisms of protein aggregation. Allosteric Modulation of protein folding by Drugs, Chaperones and Interactors. Pharmacological Modulation of Wnt signaling pathway.
Keywords: Protein Folding, Endoplasmic Reticulum, Conformational Diseases, Allostery, Wnt pathway.
Research Group 13
Donatella Tramontano
Research Themes
- Autophagy and metabolic alterations: molecular mechanisms of food antioxidants in skin and prostate systems.
Keywords: Autophagy, metabolic disorders, food antioxidant, keratinocytes, prostate cancer.
Research Group 14
Chiara Zurzolo
Research Themes
- Intracellular and Intercellular trafficking of the prion protein and prion like-proteins: the site of pathological conversion and the mechanism of spreading
- Mechanism of GPI-anchored protein sorting to the plasma membrane
Keywords: intracellular trafficking, prion diseases, nanotubes, amylodoigenic proteins, GPI-proteins.
Teaching
web page administrator: Massimo Mallardo