Università degli studi di Milano
Last Update: September 1, 2022
University Professors in Experimental Biology (BIO/13)
PROFESSOR
POSITION
AIBG
Daniela Galimberti – Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche
PA
AIBG Member
Francesco Rusconi – Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
RTD-B
AIBG Member
PO (Professore Ordinario / Full professor)
PA (Professore Associato / Associate Professor)
RTI (Ricercatore a Tempo Indeterminato / Assistant Professor)
RTD-A (Ricercatore a Tempo Determinato – Junior / Fixed-term Junior Assistant Professor)
RTD-B (Ricercatore a Tempo Determinato – Senior / Fixed-term Senior Assistant Professor)
Fellows in Experimental Biology (BIO/13)
FELLOW
POSITION
AIBG
Barbara Tedesco – Dipartimento di Scienze Farmacologiche e Biomolecolari
A
Martina Anselmi – Dipartimento di Scienze Farmacologiche e Biomolecolari
D
Paola Bettinaglio – Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
D
Alessia Brix – Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
D
Gioia Cappelletti – Dipartimento di Scienze Biomediche e Cliniche
D
Elena Casarotto – Dipartimento di Scienze Farmacologiche e Biomolecolari
D
Giuliana Cesare – Dipartimento di Bioscienze
D
Marta Chierichetti – Dipartimento di Scienze Farmacologiche e Biomolecolari
D
Marta Cozzi – Dipartimento di Scienze Farmacologiche e Biomolecolari
D
China Genchi – Dipartimento di Bioscienze
D
Alyssa Paganoni – Dipartimento di Scienze Farmacologiche e Biomolecolari
D
Paulien H. Smeele – Dipartimento di Bioscienze
D
Luis Castro – Dipartimento di Bioscienze
B
Gaia Consonni – Dipartimento di Bioscienze
B
Antonella Lettieri – Dipartimento di Scienze della Salute
B
AIBG Member
Federica Monastra – Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
B
Viviana Tritto – Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
B
AIBG Member
A (Assegnista di Ricerca / Post-Doctoral Fellow)
D (Dottorando / PhD Student)
B (Borsista / Fellow)
T (Tutor)
Research
Research Group 1
Angelo Poletti
Paola Rusmini
Valeria Crippa
Riccardo Cristofani
Margherita Piccolella (Technician)
Veronica Ferrari
Barbara Tedesco
Elena Casarotto
Marta Chierichetti
Marta Cozzi
Paola Pramaggiore
Research Themes
- Evaluation of neurotoxic effects of mutant proteins involved in motoneuron diseases.
- Identification of protective mechanisms counteracting the acumulation and facilitating the clearance of mutant misfolded proteins.
Keywords: Motoneuron diseases, autophagy, proteasome, chaperones, muscle.
- In vitro study of basic biological processes, such as cell proliferation, migration and invasiveness, of human tumors: neuroblastoma, breast and prostate cancer.
Keywords: cancer, proliferation, migration, invasiveness.
Research Group 2
Patrizia Limonta
Roberta Manuela Moretti
Fabrizio Fontana
Martina Anselmi
Research Themes
- Evaluation of the molecular mechanisms underlying the growth and progression of tumors with the aim to identify novel markers and targets for innovative and effective preventive/therapeutic strategies.
Keywords: proliferation/apoptosis, endoplasmic reticulum stress, autophagy, mitochondrial dysfunction, exosomes, stem cells.
Research Group 3
Anna Cariboni
Roberto Oleari
Alyssa Paganoni
Research Themes
- Cell and animal models (mouse, zebrafish) to study the molecular mechanisms underlying GnRH neuron development and genetic forms of reproductive failure (Kallmann and CHARGE syndromes).
Keywords: GnRH neurons, CHARGE, Kallmann, semaphorins, CHD7.
Research Group 4
Paola Riva
Viviana Tritto (Specialization School Fellow)
Paola Bettinaglio (PhD Student)
Emanuela Martinoli (Technician)
Marinella Volontè (Technician)
Research Themes
- Identification of genetics and epigenetics mechanisms involved in variable expressivity in Neurofibromatosis type 1 and Noonan syndrome
Keywords: NF1 and Noonan syndrome, RAS pathway, modifier genes, variable expressivity.
Research Group 5
Research Themes
- Role of receptor P2X7 in T cells and study of the control of autoimmune diseases.
Keywords: T lymphocyte, signal trasduction, autoimmunity, P2X7.
Research Group 6
Elena Battaglioli
Francesco Rusconi (RTD-B)
Emanuela Toffolo (Technician)
Chiara Forastieri (Post-Doctoral Fellow)
Research Themes
- Role of LSD1 as gene x environment (GxE) mediator in brain plasticity and pathophysiology of neurologic disorders.
Keywords: Epigenetics, LSD1, epilepsy, Rett syndrome, neuropsichiatric disorders.
Research Group 7
Luisa Doneda
Leda Rosalba Roncoroni (RTD-A)
Research Themes
- Characterization of intestinal, blood, mucosal microbiota and analysis of mucosal and cellular miRNAs in patients with refractory celiac disease
Keywords:
Refractory celiac disease, primary cultures, miRNAs, gliadin peptides.
- Evaluation of the activity of transglutaminase type 2 (TG2) inhibitors on duodenal mucosa of celiac subjects
Keywords:
Celiac disease, Transglutaminase type 2, TG2 inhibitors, ex-vivo cultures.
Research Group 8
Research Themes
- Role of non-coding RNAs in aging and neurodegenerative diseases
- Molecular basis of human genetic diseases.
Keywords: Non-coding RNAs, aging, senescence, neurodegenerative diseases, human genetic diseases.
Research Group 9
Anna Pistocchi
Anna Marozzi
Alex Pezzotta (Post-Doctoral Fellow)
Alessia Brix (PhD student)
Federica Monastra (Fellowship student)
Research Themes
- Zebrafish as a model system to study genes related to human diseases such as myeloid leukemia, myopathies, neuro-muscular diseases and cystic fibrosis.
Keywords: AML, zebrafish, cohesins, muscle, cystic fibrosis.
Research Group 10
Valentina Massa
Paolo Grazioli (Post-Doctoral Fellow)
Antonella Lettieri (Fellow)
Research Themes
- Central nervous system congenital malformations and related human pathology.
Keywords: Neural tube development, Cornelia de Lange syndrome, Cohesins, Genetic neurologic disorders, chromatin remodelling
Research Group 11
Mara Biasin
Irma Saulle (Technician)
Gioia Cappelletti (PhD Student)
Research Themes
- Genetic and Immunological correlates of protection in natural resistance to HIV-1 infection.
Keywords: Viruses, resistance, natural and acquired immunology, polimorphisms.
Research Group 12
Daniela Galimberti
Caterina Visconte (Post-Doctoral Fellow)
Federica Sorrentino (Post-Doctoral Fellow)
Stefano Floro (Post-Doctoral Fellow)
Chiara Fenoglio (Technician)
Research Themes
- Biomolecular mechanisms involved in neurodegenerative and demielinating diseases.
Keywords: Dementia, multiple sclerosis, epigenetics.
Research Group 13
Sara Sigismund
Chiara Tordonato
Stefano Freddi
Deborah Salvi Mesa
Research Themes
- Characterization of the mechanisms of Epidermal Growth Factor Receptor (EGFR) endocytosis, investigation of how they regulate EGFR signaling and cell biological response to EGF, and study of their alterations in cancer.
Keywords: EGFR, endocytosis, trafficking, signaling, receptor degradation, proliferation, migration, cancer.
Research Group 14
Thomas Vaccari
Francesco Lavezzari
Paulien H. Smeele
Giuliana Cesare
Luis Castro
Gaia Consonni
Research Themes
- Cell biology and genetics of membrane trafficking, signaling and development.
Keywords: Drosophila, endocytosis, notch signaling, Hh signaling, SNARES, V-ATPase, ESCRT, tumor suppression, disease models.
Research Group 16
Research Themes
- Structural and functional defects linked to the expression of Amyotrophic Lateral Sclerosis (ALS)-associated mutant proteins in cellular and animal models of ALS.
- Structure and function of central synapses from primary neuronal cultures and brains of murine models of neurodevelopmental disorders.
Keywords: synapse, dendritic spines, post-synaptic densities, neuromuscular junction, neurons, excitability, neurological disorders
Teaching
web page administrator: Marco Venturin