Giovanna Di Emidio
- Cellular adaptations to endogenous or exogenous stressors through antioxidant and antiglycative responses involving reactive oxygen species (ROS) and methylglyoxal (MG)-related pathways.
- Redox- and glycation-responsive molecular mechanisms underlying pathophysiological processes (aging, dismetabolism, neurodegenerations etc.).
- Cellular mechanisms underlying female gonadal response to oxidative and dicarbonyl stress in aging, dismetabolisms and antitumor therapies.
- Role of sirtuins and NAD+ in gametes.
- Cellular, metabolic and molecular mechanisms underlying drug resistance and reprogramming in cancer.
Keywords: reactive oxygen species (ROS), methylglyoxal (MG), hormesis, cellular adaptations, sirtuins, NAD, aging, reproduction, metabolism, oxidative stress, glycative stress, dicarbonyl stress, oocyte, drug resistance, cancer cell reprogramming.