Università degli Studi “Magna Graecia” di Catanzaro
Last Update: August 31, 2023
University Professors in Experimental Biology (BIO/13)
PROFESSOR
POSITION
AIBG
PO (Professore Ordinario / Full professor)
PA (Professore Associato / Associate Professor)
RTI (Ricercatore a Tempo Indeterminato / Assistant Professor)
RTD-A (Ricercatore a Tempo Determinato – Junior / Fixed-term Junior Assistant Professor)
RTD-B (Ricercatore a Tempo Determinato – Senior / Fixed-term Senior Assistant Professor)
Fellows in Experimental Biology (BIO/13)
FELLOW
POSITION
AIBG
Raffaella Gallo – Dipartimento di Medicina Sperimentale e Clinica
A/T
Valentina Maggisano – Dipartimento Scienze della Salute
A/T
Alessandro Sacco – External Collaborator
T
A (Assegnista di Ricerca / Post-Doctoral Fellow)
D (Dottorando / PhD Student)
B (Borsista / Fellow)
T (Tutor)
Research
Research Group 1
Flavia Biamonte
Anna Martina Battaglia
Emanuele Giorgio
Lavinia Petriaggi
Research Themes
- Molecular mechanisms underlying the redox-mediated cancer development and progression.
- Human ferritin as oncogene involved in the control of cancer hallmarks.
- Human ferritin as regulator of small non-coding RNAs.
- Ferroptosis as new mechanism of regulated cell death.
- Iron in shaping tumor microenvironment (TME).
- Generation 3D cell cultures for the characterization of tumor metabolism.
Keywords: iron, ferroptosis, cancer, oxidative stress, ferritin, small non-coding RNA.
Research Group 2
Stefania Bulotta
Marilena Celano
Valentina Maggisano
Research Themes
- Molecular and cellular mechanisms involved in the alteration of cellular differentiation and proliferation in normal and/or poorly differentiated epithelial cells.
- Molecular mechanisms and pathways involved in the regulation of tumor microenvironment (TME) in in vitro and in vivo experimental models.
- Biological effects of nutraceuticals focusing on olive oil polyphenols with antioxidant activity.
- Study on the biology of the endothelial nitric oxide synthase (eNOS) and its role in various physiological mechanisms.
Keywords: epithelial cells, gene expression, tumor microenvironment (TME), microRNA, bioactive polyphenols, antioxidant activity, eNOS, apoptosis, cellular migration.
Research Group 3
Giuseppe Fiume
Research Themes
- Analysis of mechanisms of viral and cellular transcriptional regulation upon HIV-1 infection.
- Metabolic reprogramming of tumor infiltrating T-lymphocytes within tumor microenvironment.
- Functional characterization of IBTK functions in gene expression regulation and developmental processes.
- Characterization of tumoral clones and exosomes in B-lymphoproliferative disorders by using Idiotype-binding peptides.
Keywords: HIV-1, Tat, NF-kappaB, tumor microenvironment, TIL, metabolic reprogramming, IBTK; phage display, idiotype peptides.
Research Group 4
Eleonora Cianflone
Antonio Chiefalo
Loredana Pagano
Research Themes
- Assessing new cardiomyocyte formation in the adult mammalian heart in response to wear and tear and/or injury by resident tissue-specific Cardiac Stem/Progenitor Cells (CSCs).
- Assessing regenerative biology through clonogenicity, self-renewal, multipotency and particularly myogenic potential of CSCs in vitro and in vivo.
- Generation of human organoids from human iPSCs or CSCs as in vitro model of cardiac development and diseases.
- Assessing cardiac cell senescence and the mechanisms to revert the senescent phenotype of the heart during aging.
Keywords: Cardiac Stem Cells, Cardiac regeneration, cardiac cell senescence, cardiomyocytes, myogenic differentiation.
Teaching
BIO/13 Courses thaught by teachers of other Scientific-Disciplinary Sectors
web page administrator: Prof.ssa Stefania Bulotta