Women and Men in Physical Activity

Physical activity represents a well-known approach for the prevention and treatment of cardio-metabolic diseases. In fact, several metabolic changes occur in the organism during exercise, leading to the activation of adaptive mechanisms.

These mechanisms aim to establish a new dynamic equilibrium especially at the metabolic level, which enhances health and optimize performance in elite athletes. However, exercise can have negative effects on health, e.g. on inflammatory and redox states.

Excessive training and effort could lead to chronic fatigue, muscle damage and lower performance.

Therefore, final beneficial/adverse exercise consequences are the result of the fine balance between the oxidative stress/inflammation induced by exercise that increases performance and health (hormesis), and the oxidative stress due to excessive effort that causes fatigue and muscle damage (overtraining).

In this context, this Research Topic seeks research articles and reviews on a broad range of topics in the area of “woman and man in physical activity” including:

  • Gender muscle fiber type composition
  • Gender related differences in cellular and molecular biomarkers (with particular relevance to those belonging to redox/inflammatory pathways) as a response to exercise (according to type, intensity, frequency and duration)
  • Cardiometabolic response to different exercise mode, frequency, duration and intensity according to gender
  • Gender differences in hormonal signals associated to exercise

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