Advances in Bioinformatics, Biostatistics and Omic Sciences

Luigi Donato, Simona Alibrandi, Rosalia D’Angelo, Concetta Scimone, Antonina Sidoti and Alessandra Costa

Bioinformatics, and by extension omic sciences – the collective disciplines that are dependent on the use of extensive datasets of biological information – present a challenge of data management for researchers all over the world. Big data collected as part of research projects and experiments can be complex, with several kinds of variables involved. Coupled with continuously changing bioinformatics and information technology tools, there is a need to bring a multidisciplinary approach into these fields.

Advances in Bioinformatics, Biostatistics and Omic Sciences attempts to realize an integrated approach between all omic sciences, exploring innovative bioinformatics and biostatistical methodologies which enable researchers to unveil hidden sides of biological phenomena.

This volume presents reviews on the following topics which give a glimpse of recent advances in the field:

  • New Integrated Mitochondrial DNA Bioinformatics Pipeline to Improve Quality Assessment of Putative Pathogenic Variants from NGS Experiments
  • Variant Calling on RNA Sequencing Data: State of Art and Future Perspectives
  • An innovative Gene Prioritization Pipeline for WES analyses
  • New Integrated Differential Expression Approach for RNA-Seq Data Analysis
  • Innovations in Data Visualization for Straightforward Interpretation of Nucleic Acid Omics Outcomes.

Audience

This book serves as a guide for graduate students in bioinformatics as well as researchers planning new projects as a part of their professional and academic activities.

Advances in Bioinformatics, Biostatistics and Omic Sciences

ISBN: 978-981-14-8178-9 (Print)
ISBN: 978-981-14-8180-2 (Online)
Year of Publication: 2020
DOI:10.2174/97898114818021200101

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Presentazione

Il gruppo di lavoro coordinato dalla Prof.ssa Antonina Sidoti, vice-direttore scientifico dell’Istituto e direttore del Dipartimento di Strategie biomolecolari, genetica e terapie d’avanguardia (SBGT), e costituito dai dottori Donato, Alibrandi, D’Angelo, Scimone e Costa, ha recentemente pubblicato il libro, in lingua inglese, dal titolo “Advances in Bioinformatics, Biostatistics and Omic Sciences”.

Il volume a carattere scientifico si concentra sul ruolo attuale della bioinformatica e delle scienze omiche – le discipline collettive che dipendono dall’uso di vasti set di dati di informazioni biologiche -, una delle più grandi sfide a livello mondiale dell’epoca moderna per la gestione dei dati. I big data raccolti come parte di progetti di ricerca ed esperimenti possono essere complessi, con diversi tipi di variabili coinvolte. Insieme ai più avanzati strumenti di bioinformatica ed information technology in continua evoluzione, è necessario applicare un approccio multidisciplinare in questi campi.

Il volume “Advances in Bioinformatics, Biostatistics and Omic Sciences” si prefigge lo scopo di realizzare un approccio integrato tra tutte le scienze omiche, esplorando le innovazioni nel campo della bioinformatica e delle metodologie biostatistiche, che possano consentire ai ricercatori di svelare i lati nascosti dei fenomeni biologici. Questo volume, inoltre, può essere utilizzato come guida per gli studenti laureati in bioinformatica e per i ricercatori che pianificano nuovi progetti come parte delle loro attività professionali e accademiche.

Presentation

The working group coordinated by Prof. Antonina Sidoti, deputy scientific director of the Institute and director of the Department of Biomolecular Strategies, Genetics and Advanced Therapies (SBGT), and made up of doctors Donato, Alibrandi, D’Angelo, Scimone and Costa, recently published the book, in English, entitled “Advances in Bioinformatics, Biostatistics and Omic Sciences”.

The science-based volume focuses on the current role of bioinformatics and omics sciences – the collective disciplines that depend on the use of vast datasets of biological information -, one of the greatest global challenges of the modern era for management. some data. Big data collected as part of research projects and experiments can be complex, with several kinds of variables involved. Coupled with continuously changing bioinformatics and information technology tools, there is a need to bring a multidisciplinary approach into these fields.

Advances in Bioinformatics, Biostatistics and Omic Sciences attempts to realize an integrated approach between all omic sciences, exploring innovative bioinformatics and biostatistical methodologies which enable researchers to unveil hidden sides of biological phenomena. This volume serves as a guide for graduate students in bioinformatics as well as researchers planning new projects as a part of their professional and academic activities.